Professur für Stammzell-Modelle seltener neuraler Erkrankungen

Human Induced Pluripotent Stem Cell-Derived Pericytes as Scalable and Editable Source to Study Direct Lineage Reprogramming Into Induced Neurons (2023) Menon R, Petrucci L, Lohrer B, Zhang J, Schulze M, Schichor C, Winner B, et al. Journal article Scaffold-Based (Matrigel™) 3D Culture Technique of Glioblastoma Recovers a Patient-like Immunosuppressive Phenotype (2023) Braun FK, Rothhammer-Hampl T, Lorenz J, Pohl S, Menevse AN, Vollmann-Zwerenz A, Bumes E, et al. Journal article Pathogenic SCN2A variants cause early-stage dysfunction in patient-derived neurons (2023) Asadollahi R, Delvendahl , Muff R, Tan G, Rodrieguez DG, Turan S, Russo M, et al. Journal article CRISPR/Cas9-mediated generation of hESC lines with homozygote and heterozygote p.R331W mutation in CTBP1 to model HADDTS syndrome (2023) Akdas EY, Turan S, Guhathakurta D, Ekici AB, Salar S, Lie DC, Winner B, Fejtová A Journal article, Original article Parkinson's disease or multiple system atrophy: potential separation by quantitative susceptibility mapping (2023) Marxreiter F, Lambrecht V, Mennecke A, Hanspach J, Jukic J, Regensburger M, Herrler J, et al. Journal article An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington’s disease patient neurons (2022) Krach F, Stemick J, Börstler T, Weiss A, Lingos I, Reischl S, Meixner H, et al. Journal article Generation of a homozygous and a heterozygous SNCA gene knockout human-induced pluripotent stem cell line by CRISPR/Cas9 mediated allele-specific tuning of SNCA expression (2022) Schneider Y, Turan S, Koller A, Krumbiegel M, Farrell M, Plotz S, Winkler J, Xiang W Journal article Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons (2022) van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, et al. Journal article Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients (2022) Stern S, Lau S, Manole A, Rosh I, Percia MM, Ben Ezer R, Shokhirev MN, et al. Journal article Neurometabolic Dysfunction in SPG11 Hereditary Spastic Paraplegia. (2022) Winner B, Marterstock D, Kopp C, Dörfler A, Regensburger M, Krumm L, Schmidt M, et al. Journal article