Lehrstuhl für Pharmazeutische Chemie

The bulky N(6) substituent of cabergoline is responsible for agonism of this drug at serotonin 5-HT2a and 5-HT2b receptors and thus a determinant of valvular heart disease (2011) Kekewska A, Hübner H, Gmeiner P, Pertz HH Journal article Structure and function of an irreversible agonist-ß2 andrenoceptor complex (2011) Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, et al. Journal article, Original article Radical arylation of tyrosine and its application in the synthesis of a highly selective neurotensin receptor 2 ligand (2011) Pratsch G, Unfried JF, Einsiedel J, Plomer M, Hübner H, Gmeiner P, Heinrich M Journal article, Original article On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum - Neurotensin, opiorphin, B27-KK10 epitope, NPY (2011) Seebach D, Lukaszuk A, Patora-Komisarska K, Podwysocka D, Gardiner J, Ebert MO, Reubi JC, et al. Journal article, Original article The bulky N(6) substituent of cabergoline is responsible for agonism of this drug at 5-hydroxytryptamine (5-HT)2A and 5-HT2B receptors and thus is a determinant of valvular heart disease (2011) Kekewska A, Hübner H, Gmeiner P, Pertz HH Journal article, Original article Histidine 6.55 is a major determinant of ligand-biased signaling in dopamine D2L receptor (2011) Tschammer N, Bollinger S, Kenakin T, Gmeiner P Journal article, Original article Aromatic ring functionalization of benzolactam derivatives: New potent dopamine D3 receptor ligands (2011) Ortega R, Hübner H, Gmeiner P, Masaguer CF Journal article, Original article A highly efficient type I β-turn mimetic simulating an asx-pro-turn-like structure (2011) Pinsker A, Einsiedel J, Härterich S, Waibel R, Gmeiner P Journal article, Original article Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides (2011) Kaßler K, Meier J, Eichler J, Sticht H Journal article Novel pyridylmethylamines as highly selective 5-HT1A superagonists (2010) Bollinger S, Hübner H, Heinemann FW, Meyer K, Gmeiner P Journal article, Original article