Lehrstuhl für Biotechnik (Proteinstruktur und -design)

PRISEs (progesterone 5β-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism. (2018) Schmidt K, Petersen J, Munkert J, Egerer-Sieber C, Hornig M, Muller Y, Kreis W Journal article Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. (2018) Schmidt K, Gardill B, Kern A, Kirchweger P, Börsch M, Muller Y Journal article, Original article Hydration Structure and Dynamics of Inhibitor-Bound HIV-1 Protease. (2018) Leidner F, Kurt YN, Paulsen J, Muller Y, Schiffer C Journal article Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis. (2018) Bartoschik T, Galinec S, Kleusch C, Walkiewicz K, Breitsprecher D, Weigert S, Muller Y, et al. Journal article Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica (2017) Peters B, Stein J, Klingl S, Sander N, Sandmann A, Taccardi N, Sticht H, et al. Journal article, Original article Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica (2017) Peters B, Stein J, Klingl S, Sander N, Sandmann A, Taccardi N, Sticht H, et al. Journal article, Original article Nuclear trafficking of the anti-apoptotic Coxiella burnetii effector protein AnkG requires binding to p32 and Importin-alpha 1 (2017) Schäfer W, Eckart R, Schmid B, Cagkoeylue H, Hof K, Muller Y, Amin B, Lührmann A Journal article Similarities in the structure of the transcriptional repressor AmtR in two different space groups suggest a model for the interaction with GlnK (2017) Sevvana M, Hasselt K, Grau F, Burkovski A, Muller Y Journal article, Original article The human cytomegalovirus IE1 protein antagonizes PML nuclear body-mediated intrinsic immunity via the inhibition of PML de novo SUMOylation (2017) Schilling EM, Scherer M, Reuter N, Schweininger J, Muller Y, Stamminger T Journal article, Original article Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83 (2017) Heilingloh C, Klingl S, Egerer-Sieber C, Schmid B, Weiler S, Mühl-Zürbes P, Hofmann J, et al. Journal article, Original article