Lehrstuhl für Biotechnik (Proteinstruktur und -design)

The human cytomegalovirus nuclear egress complex unites multiple functions: Recruitment of effectors, nuclear envelope rearrangement, and docking to nuclear capsids (2017) Marschall M, Muller Y, Diewald B, Sticht H, Milbradt J Journal article, Review article Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors. (2016) Fillenberg S, Frieß M, Körner S, Böckmann R, Muller Y Journal article, Original article Nuclear trafficking of the anti-apoptotic Coxiella burnetii effector protein AnkG requires binding to p32 and Importin-α1 (2016) Schäfer W, Eckart R, Schmid B, Cagköylü H, Hof K, Muller Y, Amin B, Lührmann A Journal article, Original article Expression, crystallization and structure elucidation of γ-terpinene synthase from Thymus vulgaris (2016) Rudolph K, Parthier C, Egerer-Sieber C, Geiger D, Muller Y, Kreis W, Müller-Uri F Journal article, Original article Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein (2015) Klingl S, Scherer M, Stamminger T, Muller Y Journal article, Original article Characterization of recombinant human cytomegaloviruses encoding IE1 mutants L174P and 1-382 reveals that viral targeting of PML bodies perturbs both intrinsic and innate immune responses (2015) Scherer M, Otto V, Stump J, Klingl S, Müller R, Reuter N, Muller Y, et al. Journal article, Original article Crystal structure of the human cytomegalovirus pUL50-pUL53 core nuclear egress complex provides insight into a unique assembly scaffold for virus-host protein interactions (2015) Walzer S, Egerer-Sieber C, Sticht H, Sevvana M, Hohl K, Milbradt J, Muller Y, Marschall M Journal article, Original article Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR (2015) Fillenberg S, Grau F, Seidel G, Muller Y Journal article, Original article Multiple allosteric effectors control the affinity of DasR for its target sites (2015) Tenconi E, Urem M, Świątek-Połatyńska MA, Titgemeyer F, Muller Y, van Wezel G, Rigali S Journal article, Original article Truncation of N-terminal regions of Digitalis lanata progesterone 5β-reductase alters catalytic efficiency and substrate preference (2014) Rudolph K, Bauer P, Schmid B, Müller-Uri F, Kreis W Journal article, Original article