The Institute of Cancer Research (ICR)

Reply to: Germline and Somatic BRCA1/2 Mutations in Breast Cancer Treatment Strategies (2025) Hahnen E, Hauke J, Gelmon K, Marmé F, Ernst C, Martin M, Untch M, et al. Journal article, Letter BRCA1/2 and Other Predisposition Genes in High-Risk Hormone Receptor+/Human Epidermal Growth Factor Receptor 2-Breast Cancer Treated with Endocrine Therapy with or Without Palbociclib: A Secondary PENELOPE-B Study Analysis (2025) Hahnen E, Hauke J, Gelmon K, Marmé F, Ernst C, Martin M, Untch M, et al. Journal article Dynamics of molecular heterogeneity in high-risk luminal breast cancer—From intrinsic to adaptive subtyping (2025) Denkert C, Rachakonda S, Karn T, Weber K, Martin M, Marmé F, Untch M, et al. Journal article Sequential ATR and PARP inhibition overcomes acquired DNA damaging agent resistance in pancreatic ductal adenocarcinoma (2025) Herbert KJ, Upstill-Goddard R, Dreyer SB, Rebus S, Pilarsky C, Debabrata M, Lord CJ, et al. Journal article Correction to: Genetic drivers and cellular selection of female mosaic X chromosome loss (Nature, (2024), 631, 8019, (134-141), 10.1038/s41586-024-07533-7) (2024) Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat SM, Kentistou KA, Yang Z, et al. Journal article, Erratum Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction (2024) Yiangou K, Mavaddat N, Dennis J, Zanti M, Wang Q, Bolla MK, Abubakar M, et al. Journal article METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII (2024) Kocak B, Akinci D’Antonoli T, Mercaldo N, Alberich-Bayarri A, Baessler B, Ambrosini I, Andreychenko AE, et al. Journal article Final analysis of the ALTTO trial: adjuvant trastuzumab in sequence or in combination with lapatinib in patients with HER2-positive early breast cancer [BIG 2-06/NCCTG N063D (Alliance)] (2024) de Azambuja E, Piccart-Gebhart M, Fielding S, Townend J, Hillman DW, Colleoni M, Roylance R, et al. Journal article Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma (2024) Saner FA, Takahashi K, Budden T, Pandey A, Ariyaratne D, Zwimpfer TA, Meagher NS, et al. Journal article Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer (2024) Jahangir CA, Page DB, Broeckx G, Gonzalez CA, Burke C, Murphy C, Reis-Filho JS, et al. Journal article, Review article