Prof. Dr. Jürgen Winkler

Professur für Molekulare Neurologie

Generation of a homozygous and a heterozygous SNCA gene knockout human-induced pluripotent stem cell line by CRISPR/Cas9 mediated allele-specific tuning of SNCA expression (2022) Schneider Y, Turan S, Koller A, Krumbiegel M, Farrell M, Plotz S, Winkler J, Xiang W Journal article Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons (2022) van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, et al. Journal article Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients (2022) Stern S, Lau S, Manole A, Rosh I, Percia MM, Ben Ezer R, Shokhirev MN, et al. Journal article Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia (2022) Utz K, Kohl Z, Marterstock D, Dörfler A, Winkler J, Schmidt M, Regensburger M Journal article Neurometabolic Dysfunction in SPG11 Hereditary Spastic Paraplegia. (2022) Winner B, Marterstock D, Kopp C, Dörfler A, Regensburger M, Krumm L, Schmidt M, et al. Journal article CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy (2022) Battis K, Florio JB, Mante M, Lana A, Naumann I, Gauer C, Lambrecht V, et al. Journal article The Gut–Immune–Brain Axis: An Important Route for Neuropsychiatric Morbidity in Inflammatory Bowel Disease (2022) Masanetz RK, Winkler J, Winner B, Günther C, Süß P Journal article, Review article Connecting real-world digital mobility assessment to clinical outcomes for regulatory and clinical endorsement–the Mobilise-D study protocol (2022) Mikolaizak AS, Rochester L, Maetzler W, Sharrack B, Demeyer H, Mazzà C, Caulfield B, et al. Journal article Inertial Gait Sensors to Measure Mobility and Functioning in Hereditary Spastic Paraplegia A Cross-sectional Multicenter Clinical Study (2022) Regensburger M, Spatz I, Ollenschläger M, Martindale C, Lindeburg P, Kohl Z, Eskofier B, et al. Journal article Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease (2022) Schmidt S, Luecken MD, Truembach D, Hembach S, Niedermeier KM, Wenck N, Pfluegler K, et al. Journal article