Dr. Harald Hübner

Lehrstuhl für Pharmazeutische Chemie

An allosteric modulator binds to a conformational hub in the beta(2) adrenergic receptor (2020) Liu X, Kaindl J, Korczynska M, Stößel A, Dengler D, Stanek M, Hübner H, et al. Journal article Red-Emitting Dibenzodiazepinone Derivatives as Fluorescent Dualsteric Probes for the Muscarinic Acetylcholine M-2 Receptor (2020) She X, Pegoli A, Gruber CG, Wifling D, Carpenter J, Hübner H, Chen M, et al. Journal article Regiospecific Introduction of Halogens on the 2-Aminobiphenyl Subunit Leading to Highly Potent and Selective M3 Muscarinic Acetylcholine Receptor Antagonists and Weak Inverse Agonists (2020) Fischer O, Hofmann J, Rampp H, Kaindl J, Pratsch G, Bartuschat A, Taudte V, et al. Journal article Investigation of Inactive-State κ Opioid Receptor Homodimerization via Single-Molecule Microscopy Using New Antagonistic Fluorescent Probes (2020) Drakopoulos A, Koszegi Z, Lanoiselée Y, Hübner H, Gmeiner P, Calebiro D, Decker M Journal article Stepwise dosing protocol for increased throughput in label-free impedance-based GPCR assays (2020) Stolwijk JA, Mildner AK, Kade C, Skiba M, Bernhardt G, Buschauer A, Hübner H, et al. Journal article Selective and Wash-Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single-Molecule Imaging of mu-Opioid Receptor Dimerization (2020) Gentzsch C, Seier K, Drakopoulos A, Jobin ML, Lanoiselee Y, Koszegi Z, Maurel D, et al. Journal article Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity. (2020) Keller M, Mahuroof SA, Hong Yee V, Carpenter J, Schindler L, Littmann T, Pegoli A, et al. Journal article, Original article Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy (2019) Xu J, Hu Y, Kaindl J, Risel P, Hübner H, Maeda S, Niu X, et al. Journal article Structure-based exploration of an allosteric binding pocket in the NTS1 receptor using bitopic NT(8-13) derivatives and molecular dynamics simulations (2019) Kling R, Burchardt C, Einsiedel J, Hübner H, Gmeiner P Journal article Development of covalent antagonists for beta 1-and beta 2-adrenergic receptors (2019) Schwalbe T, Hübner H, Gmeiner P Journal article