Dr. rer. nat. Clara Dees

Department of Medicine 3 – Rheumatology and Immunology

JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment (2017) Zhang Y, Liang R, Chen CW, Mallano T, Dees C, Distler A, Reich A, et al. Journal article Nintedanib macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis (2017) Huang J, Maier C, Zhang Y, Soare A, Dees C, Beyer C, Harre U, et al. Journal article The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis (2017) Bergmann C, Brandt A, Merlevede B, Hallenberger L, Dees C, Wohlfahrt T, Pötter S, et al. Journal article Type 2 Innate Lymphoid Cells - Cellular Source of Profibrotic Mediators Rapidly and Persistently Recruited in Experimental Fibrosis and Systemic Sclerosis (2016) Weber S, Wohlfahrt T, Rauber S, Luber M, Englbrecht M, Dees C, Beyer C, et al. Conference contribution Jumonji Domain Containing Protein 3 (JMJD3) As a Novel Epigenetic Mechanism of Fibroblast Activation By Regulation of Fra-2 (2016) Bergmann C, Brandt A, Dees C, Zhang Y, Lin NY, Chen CW, Mallano T, et al. Conference contribution Fibroblast Growth Factor 9/Fibroblast Growth Factor Receptor 3 Signaling Is Upstream of Several Profibrotic Pathways and Induces Fibroblast Activation and Tissue Fibrosis in SSc (2016) Mallano T, Distler A, Dees C, Huang J, Distler O, Schett G, Distler J, Chakraborty D Conference contribution FRA2 IS PLAYING A KEY ROLE IN THE CONTROL OF TREG DEVELOPMENT AND AUTOIMMUNITY (2016) Renoux F, Stellato M, Pachera E, Impellizzieri D, Dees C, Distler J, Kania G, et al. Conference contribution Dipeptidyl-Peptidase-4 (DPP4) Positive Fibroblast Subpopulation Promotes Fibrosis and Are a Molecular Target for Treatment of Fibrosis (2016) Soare A, Rauber S, Wohlfahrt T, Dees C, Liang R, Zhang Y, Chen CW, et al. Conference contribution THE HOMEOPROTEIN ENGRAILED-1 REGULATES CANONICAL TGF-beta SIGNALING VIA FIBROBLAST DIFFERENTIATION AND TISSUE FIBROSIS (2016) Mallano T, Palumbo-Zerr K, Beyer C, Dees C, Huang J, Wohlfahrt T, Distler O, et al. Conference contribution TYPE 2 INNATE LYMPHOID CELLS ARE RAPIDLY AND PERSISTENTLY RECRUITED IN EXPERIMENTAL FIBROSIS AND THEIR COUNTS CORRELATE WITH THE SEVERITY OF SKIN AND LUNG FIBROSIS IN SYSTEMIC SCLEROSIS (2016) Wohlfahrt T, Weber S, Englbrecht M, Dees C, Beyer C, Distler O, Schett G, et al. Conference contribution