Prof. Dr. med. Kai-Uwe Eckardt

Department of Medicine 4 – Nephrology and Hypertension Lehrstuhl für Innere Medizin IV

The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment (2012) Wang Z, Schley G, Türkoglu G, Burzlaff N, Amann KU, Willam C, Eckardt KU, Bernhardt WM Journal article, Original article Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues (2012) Schley G, Klanke B, Schödel J, Kroening S, Türkoglu G, Beyer A, Hagos Y, et al. Journal article, Original article Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury (2011) Schley G, Klanke B, Schödel J, Forstreuter F, Shukla D, Kurtz A, Amann KU, et al. Journal article The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis (2011) Buchholz B, Klanke B, Schley G, Bollag G, Tsai J, Kroening S, Yoshihara D, et al. Journal article, Original article Formation of cysts by principal-like MDCK cells depends on the synergy of cAMP- and ATP-mediated fluid secretion (2011) Buchholz B, Teschemacher B, Schley G, Schillers H, Eckardt KU Journal article, Original article Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells (2010) Schödel J, Bohr D, Klanke B, Schley G, Schlötzer-Schrehardt U, Warnecke C, Kurtz A, et al. Journal article The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in Hypoxia: Insights into cellular transformation processes mediated by HIF-1 (2010) Schietke R, Warnecke C, Wacker I, Schödel J, Mole DR, Campean V, Amann KU, et al. Journal article Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1 (2010) Gimm T, Wiese M, Teschemacher B, Deggerich A, Schödel J, Knaup K, Hackenbeck T, et al. Journal article Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model (2009) Bernhardt WM, Gottmann U, Doyon F, Buchholz B, Campean V, Schödel J, Reisenbuechler A, et al. Journal article HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia (2009) Hackenbeck T, Knaup K, Schietke R, Schödel J, Willam C, Wu X, Warnecke C, et al. Journal article, Report