PD Dr. Heiko Bruns

Department of Medicine 5 – Haematology and Oncology

Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection (2021) Spoerl S, Kremer A, Aigner M, Eisenhauer N, Koch P, Meretuk L, Loeffler P, et al. Journal article The IKZF1–IRF4/IRF5 axis controls polarization of myeloma-associated macrophages (2021) Mougiakakos D, Bach C, Böttcher M, Beier F, Röhner L, Stoll A, Rehli M, et al. Journal article CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity (2021) Stoll A, Bruns H, Fuchs M, Nimmerjahn F, Kunz M, Peipp M, Mackensen A, et al. Journal article Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis (2021) Böttcher M, Bruns H, Völkl S, Lu J, Chartomatsidou E, Papakonstantinou N, Mentz K, et al. Journal article The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts (2021) Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp S, Walker KI, et al. Journal article, Original article Selective elimination of immunosuppressive T cells in patients with multiple myeloma (2021) Awwad MHS, Mahmoud A, Bruns H, Echchannaoui H, Kriegsmann K, Lutz R, Raab MS, et al. Journal article beta(2)-microglobulin - a trigger for NLRP3 inflammasome activation in tumor-associated macrophages promoting multiple myeloma cell progression (2020) Hofbauer D, Mougiakakos D, Ricagno S, Buettner-Herold M, Neumann F, Bisht S, Zeiser R, et al. Conference contribution Immune cell regulation by vitamin D-3 during allogeneic hematopoietic stem cell transplantation (HSCT) (2020) Flamann C, Zeun J, Kremer A, Peter K, Kreutz M, Büttner-Herold M, Kellner C, et al. Conference contribution Stroma cells promote a S100A8/A9(high) subset of chemoresistant AML blasts with distinct metabolic features in a Jak/STAT-dependent manner (2020) Böttcher M, Panagiotidis K, Mentz K, Popp S, Geyh S, Jaeger P, Schroeder T, et al. Conference contribution Stromal cells enhance PD-L1 expression on CLL cells via the oncogenic Notch-cMyc-EZH2 signaling axis (2020) Böttcher M, Mentz K, Popp S, Saul D, Bruns H, Mackensen A, Mougiakakos D, Völkl S Conference contribution