Dr. rer. nat. Gloria Lutzny-Geier

Department of Medicine 5 – Haematology and Oncology

Exploring CAR T-Cell Dynamics: Balancing Potent Cytotoxicity and Controlled Inflammation in CAR T-Cells Derived from Systemic Sclerosis and Myositis Patients (2025) Dingfelder J, Taubmann J, von Heydebrand F, Aigner M, Bergmann C, Knitza J, Park S, et al. Journal article Novel co-culture model of T cells and midbrain organoids for investigating neurodegeneration in Parkinson’s disease (2025) Gerasimova E, Beenen A, Kachkin D, Regensburger M, Zundler S, Blumenthal DB, Lutzny-Geier G, et al. Journal article, Original article Fully Human Anti-CD19 CAR T Cells Derived from Systemic Lupus Erythematosus Patients Exhibit Cytotoxicity with Reduced Inflammatory Cytokine Production (2024) Dingfelder J, Aigner M, Taubmann J, Minopoulou I, Park S, Kaplan CD, Cheng JK, et al. Journal article Targeted inhibition of protein synthesis renders cancer cells vulnerable to apoptosis by unfolded protein response (2023) Gsottberger F, Meier C, Ammon AM, Parker S, Wendland K, George R, Petkovic S, et al. Journal article Block of Counter-Regulation By Inhibition of Protein Synthesis Sensitizes Cancer Cells to IRE1a-Mediated Apoptosis Following Unfolded Protein Response (2022) Gsottberger F, Meier C, Ammon AM, Parker S, Wendland K, George R, Petkovic S, et al. Conference contribution Targeted Inhibition of Protein Biosynthesis sensitizes Cancer Cells to IRE1a-mediated Apoptosis as a Consequence of the unfolded protein response (2022) Gsottberger F, Meier C, Ammon AM, Parker S, Wendland K, George R, Petkovic S, et al. Conference contribution Successful Generation of CD19 Chimeric Antigen Receptor T Cells from Patients with Advanced Systemic Lupus Erythematosus (2022) Kretschmann S, Völkl S, Reimann H, Krönke G, Schett G, Achenbach S, Lutzny-Geier G, et al. Journal article Effect of Idelalisib on PKC beta/NF-kappa B regulation in stromal cells of chronic lymphocytic leukemia (2021) Lutzny-Geier G, Handl SA, Von Heydebrand F, Wilke J, Kremer AL, Mackensen A, Völkl S Conference contribution Severity of COVID-19 disease is related to hyperactivation and altered migratory capacity of T cells (2021) Spörl S, Kremer AL, Aigner M, Eisenhauer N, Koch P, Meretuk L, Loeffler P, et al. Conference contribution Successful treatment of COVID-19 with convalescent plasma in B-cell depleted patients may promote cellular immunity (2021) Kremer A, Kremer A, Willam C, Verhagen J, Achenbach S, Van Der Meiden E, Lang V, et al. Conference contribution