P033 (Biochemie, Mol. Medizin): The role of the transcription factor YB-1 in molecular regulation of chondrogenesis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 26.03.2019
End date : 25.03.2020
Project details
Scientific Abstract
YB-1 is expressed in chondrocytes during late embryonic stages and after birth, suggesting a crucial role of YB-1 in chondrogenesis. Little is known about signaling cascades linked to YB-1 mediating ist action. The goal of this study is to investigate YB-1-dependent pathways during chondrogenesis. Particular interest will be paid to MIA-dependent signaling (upstream) and target genes involved in transition to hypertrophy and dedifferentiation (downstream).
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Lehrstuhl für Biochemie und Molekulare Medizin
Medizinische Fakultät
