P059: Regional inflammatory susceptibility of the central nervous system in rheumatoid arthritis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.03.2020
End date : 28.02.2021
Extension date: 30.11.2021
Project details
Scientific Abstract
Rheumatoid arthritis (RA) is linked to neuropsychiatric comorbidity like depression due to inflammatory brain involvement. This project aims to investigate the influence of chronic peripheral inflammation on the blood brain-barrier and macrophages in different brain regions in an RA mouse Modell and human post mortem tissue. Thereby, local factors promoting inflammatory susceptibility or resilience may be identified as therapeutic targets for the CNS involvement in RA.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Molecular Neurology
Medizinische Fakultät
