P073: Pericyte-dependent impairment of blood-brain-barrier and therapeutic strategies in intracerebral hemorrhage
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.05.2021
End date : 15.05.2022
Project details
Scientific Abstract
Pericytes are small cells around brain capillaries and play a major role in maintenance of the blood brain barrier. In intracerebral hemorrhage (ICH), blood products induce complex processes leading to dysfunction of pericytes, impairment of the blood brain barrier and perihemorrhagic edema (PHE) formation. Aim of this study is to identify the blood metabolites triggering pericyte dysfunction to develop treatment strategies against PHE formation and to improve functional outcome of ICH patients.
Involved:
Contributing FAU Organisations:
Department of Neurology
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Medizinische Fakultät
