J087: Stromal Network Communication in the Regulation of Immune Homeostasis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.01.2021
End date : 15.01.2022
Extension date: 30.06.2023
Project details
Scientific Abstract
I could previously identify resident tissue macrophages (RTM) as anti-inflammatory protectors of stromal integrity. The molecular mechanisms that regulate this tissue-protective function, however, are unknown. My preliminary work strongly suggests that within stromal tissues exist extensive, heterocellular communication networks. I hypothesize that functional network communication between stromal fibroblasts and RTM coordinate biological behavior of tissues and facilitate RTM functionality.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
Medizinische Fakultät
