P075: Elucidate how cell-type specific CD109 expression influences cellular functions
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.04.2021
End date : 15.04.2022
Project details
Scientific Abstract
Cluster of Differentiation 109 (CD109) is a cell surface protein that is GPI anchored in the cell membrane. It belongs to the ?2-macroglobulin, C3, C4, C5 protein family and is expressed on keratinocytes, platelets, immune stem cells as well as CD4 and CD8 positive T-cells. In recent years CD109 was also described as risk factor for several tumour entities. In this project we will elucidate the interactome of CD109 on the cell surface and evaluate resulting cell- type specific changes.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Lehrstuhl für Funktionelle und Klinische Anatomie
Medizinische Fakultät
