P088: Role of IL-18 in the myocardial connexin 43 translocation after trauma
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.10.2021
End date : 15.10.2022
Project details
Scientific Abstract
Trauma is the leading cause of death in humans aged below 45. Trauma can affect everyone, everywhere at any time. Blunt cardiac injury is associated with increased mortality after trauma. Redistribution of the gap junction protein Connexin43 is associated with cardiac dysfunction. In the present project, important new molecular insights into the regulation of Cx43 in the heart after trauma will be revealed and may identify therapeutic targets for preservation of cellular coupling.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Professur für Traumaimmunologie
Medizinische Fakultät
