IZKF-N8 Lysosomes & glial cells: Lysosomal dysfunction within glial cells

FAU own research funding: EFI / IZKF / EAM ...


Start date : 16.02.2021

End date : 15.02.2023

Extension date: 15.11.2024


Project details

Scientific Abstract

Recent studies suggest that glial dysfunction significantly contributes to neurodegeneration in Parkinson?s disease (PD). Since lysosomal degradation is important for glial cell function, we aim to analyse the molecular consequences of lysosomal dysfunction within different glial cell lines. A better understanding of glial regulation and lysosomal turnover will help to unravel molecular mechanisms in PD and might facilitate the identification of novel therapeutic strategies in PD.

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