P093: Vascularizing engineered cardiac tissues based on collagen hydrogels mimicking native extracellular matrix
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.09.2021
End date : 31.12.2022
Project details
Scientific Abstract
We aim at generating multicellular engineered tissues based on hiPSC-derived endothelial cells and cardiomyocytes in a collagen-based hydrogel mimicking the fibrous structure of the native cardiac matrix. We will determine whether such hydrogels provide a proper environment to enhance pre-vascularization utilizing hiPSC-derived endothelial cells and whether cardiomyocyte maturation as well as pre-vascularization is enhanced in 3D engineered multicellular cardiac tissues.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Nephropathology
Medizinische Fakultät
