P106: Diet-induced function of Aryl hydrocarbon Receptor (AhR) during establishment of the humoral immune response
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.09.2022
End date : 31.08.2023
Project details
Scientific Abstract
The aim of the intended research project is to investigate the role of the transcription factor AhR in B-cells in the establishment of an antigen-specific humoral immune response. Therefore, B cell-specific AhR-deficient mice and control animals will be 1. immunized in a T-cell-dependent manner while fed a diet containing AhR ligands and 2. their B cells will be activated in vitro and analyzed in detail. In addition, AhR target genes in B cells will be determined (RNASeq)
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Molecular Immunology
Medizinische Fakultät
