P111: Regulation and function of ferroptosis in epithelial restitution and recovery from intestinal inflammation
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.11.2022
End date : 31.10.2023
Project details
Scientific Abstract
A strict cell death regulation is indispensable for the maintenance of intestinal homeostasis, since increased cell death is able to trigger intestinal inflammation. Our newly planned experiments can help to discover the impact of the gluthathione peroxidase GPX4 on the regulation of ferroptotic cell death, as well as the induction and maintenance of intestinal inflammation. GPX4 might display a potential target for new therapeutic strategies.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Medizinische Fakultät
