A096: Molecular and functional analysis of immune/ intestinal epithelial cell-interaction during CMV infection
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.01.2023
End date : 30.06.2025
Project details
Scientific Abstract
Reactivation of latent Cytomegalovirus (CMV) infections represent a severe, life-threatening intestinal complication in immunocompromised patients. Underlying cellular and molecular mechanisms regulating the immune epithelial cell interaction are only partially understood and targeted treatment options are not available. We seek to decipher the immune / epithelial cell interaction in the context of CMV infection combining novel ex vivo organoid co-culture with innovative genetic model systems
Involved:
Thomas Winkler
Project Leader
Kai Hildner
Project Leader
Marco Thomas
Project Member
Maike Büttner-Herold
Project Member
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Institute of Clinical and Molecular Virology
Professur für Genetik
Department of Nephropathology
Professur für Mukosale Immuntherapie
Medizinische Fakultät
