E036: Establishment of neuronal diversity of midbrain dopaminergic neurons by temporal patterning
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2023
End date : 30.11.2025
Extension date: 31.12.2025
Project details
Scientific Abstract
Parkinsons disease is a neurodegenerative movement disorder characterized by the progressive loss of midbrain dopaminergic (mDA) neurons. mDA neurons can be partitioned into numerous molecularly and functionally distinct neuronal subtypes. The molecular mechanisms orchestrating mDA neuron subtype specification are still largely unclear. This project will test the hypothesis that a temporal patterning program I recently uncovered contributes to the establishment of mDA neuron diversity.
Involved:
Contributing FAU Organisations:
Lehrstuhl für Biochemie und Pathobiochemie
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Juniorprofessur für Translationale Neurowissenschaften
Medizinische Fakultät
