P132: Identification of metabolic checkpoints during osteoclastogenesis and bone turnover

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.03.2024

End date : 28.02.2025

Extension date: 31.08.2025


Project details

Scientific Abstract

Osteoclasts (OCs) play key roles in the regulation of bone mass and excessive osteoclastogenesis is involved in joint destruction in autoimmune arthritis or osteoporosis. The current knowledge on cellular metabolism and its impact on OC function and bone homeostasis remain unclear. In this project, we aim to characterize metabolic dynamics during osteoclastogenesis and to identify novel regulators of bone turnover.

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