P047: Synaptic Plasticity in Human Hippocampal Subfields in Temporal Lobe Epilepsy
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.06.2019
End date : 15.12.2020
Project details
Scientific Abstract
Synaptic plasticity refers to activity-dependent strengthening or weakening of synaptic transmission and underlies memory formation. It can be investigated in-vitro by repetitive network stimulation. In patients with temporal lobe epilepsy, affecting the memory-related hippocampal formation, deficits in memory can occur. We aim to investigate the link between synaptic plasticity and memory impairment by in-vitro field potential recordings from human hippocampus removed during epilepsy surgery.
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Neurosurgery
Medizinische Fakultät
