P137: Spatial interactions of disease-relevant T-cell clones in Rheumatoid Arthritis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.04.2024
End date : 31.01.2025
Project details
Scientific Abstract
RA is a chronic inflammatory autoimmune disease that results in hyperplasia of synovial membrane of joints. However, little is known about the molecular profile and heterogeneity of infiltrating immune cells as well as about the molecular features of their cell-cell interactions. The aim of this project is to generate combined datasets on the molecular features and spatial distribution of resident and infiltrating immune cells via spatial transcriptomics of synovial tissue biopsies.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
Medizinische Fakultät
