P145: Impaired local and systemic Th17/Treg immune response in periodontitis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2024
End date : 30.06.2025
Extension date: 31.12.2025
Project details
Scientific Abstract
Periodontitis (PA) is a highly prevalent disease that has bidirectional associations with Diabetes and Alzheimer's disease. PA is leading to irreversible destruction of tooth-surrounding tissues and tooth loss. The pathogenesis of PA is poorly understood. Aim is the analysis of possible Th17/Treg disbalance in PA, association with pro- and anti-inflammatory cytokines, and whether these alterations are local or systemic. The goal is to identify biomarkers and potential targets for immunotherapy.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Operative Dentistry and Periodontology
Medizinische Fakultät
