FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.10.2021
End date : 30.09.2022
In patients with periodontitis, orofacial clefts and partly also during orthodontic treatment an oral dysbiosis and an increase of inflammation markers have been observed. Here, for the first time a systematic analysis of the oral microbiome and local inflammation in oral niches will be carried out using 16S rDNA sequencing and multiplex immuno assay, which will be correlated with determinants such as gingivitis/periodontitis, age, orofacial clefts, exogeneous factors and orthodontic treatment.