IZKF-P062: Functional relevance of CD83 expressed by macrophages for tissue homeostasis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 15.01.2020
End date : 14.01.2021
Project details
Scientific Abstract
Tissue-resident macrophages (tirM?) contribute to steady state physiology in tissues but also modulate and terminate inflammatory processes. Gene expression data revealed that CD83, a molecule with potent immunoregulatory properties, is highly expressed in tirM?. However, the biological relevance of CD83 expression by macrophages is poorly understood. Thus, this project aims to elucidate the role and regulation of CD83 in tirM? and in macrophages under pro- and anti-inflammatory conditions.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Immune Modulation
Medizinische Fakultät
