P067: Investigation of the immune-oncological characteristics of breast cancer with DNA repair deficiency
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.12.2020
End date : 31.12.2021
Project details
Scientific Abstract
DNA damage repair deficiency is common in triple-negative breast cancer, especially in the presence of BRCA1/2 mutations, and is associated with a higher mutational load and immunogenicity. In this project, multi-spectral imaging will be used to investigate the spatial distribution of different immune cells in specimens of triple-negative tumors from 40 patients (BRCA1+, BRCA2+, WT) and their influence on clinical parameters.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Obstetrics and Gynaecology
Medizinische Fakultät
