P081: Role of amino acid transporter SNAT1/SLC38A1 in human melanoma
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.05.2023
End date : 30.04.2024
Project details
Scientific Abstract
SNAT1 mediates the transport of neutral amino acids into the cell. Preliminary data show a significant overexpression of SNAT1 in human melanoma cells compared to melanocytes. Transient downregulation of SNAT1 resulted in significant reduction of the cellular proliferation and cell cycle progression. With this project we aim to analyze the functional importance of SNAT1, an attractive therapeutic target, in human melanoma.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Lehrstuhl für Biochemie und Molekulare Medizin
Medizinische Fakultät
