P159: Investigating the Impact of Indirect Pulp Capping on Dental Pulp Cells: An In Vitro 3D-Model Exploration
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.06.2025
End date : 31.05.2026
Project details
Scientific Abstract
Indirect capping of the dental pulp is recommended in deep cavities, but there is little clinical evidence for the success of the procedure. In an innovative simulation model of the pulp-dentin-complex, the effect of different biocompatible capping materials on human pulp cells through a dentin barrier will be tested. By analyzing cell survival, gene expression, oxidative stress and cytokine production, their bioactive effects will be compared in a way that is not possible in vivo.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Operative Dentistry and Periodontology
