IZKF-S1 Train (Physiologie): TRAIN: Towards Rationalizing Neurodevelopment

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.01.2024

End date : 31.12.2025


Project details

Scientific Abstract

During central nervous system development cells undergo a series of decisions to ultimately form highly specialized networks – the structural basis for behavior and cognition. This developmental decision-making process is poorly understood, yet of high clinical relevance as its disruption can result in neurodevelopmental disorders and loss of resilience to disease in later life. The Synergy Project “TRAIN: Towards Rationalizing Neurodevelopment” pursues a novel concept that key decisions in neurodevelopment are controlled by biological ratios. In TRAIN, experts in neurodevelopment, artificial intelligence, bioinformatics, and optogenetic engineering join forces to generate tools for prediction, genetic manipulation, and high-content analyses of ratios driving neurodevelopmental decisions. Hence, TRAIN will create a truly interdisciplinary research environment allowing to drill deep into the mechanisms of central nervous system development.

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Contributing FAU Organisations: