P136: Deciphering the effects of tyrosine kinase inhibitor therapy on bone metabolism and longitudinal growth

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.01.2025

End date : 31.12.2025


Project details

Scientific Abstract

As a result of non-specific inhibition, tyrosine kinase inhibitors (TKIs) also affect bone and cartilage development. Children and adolescents therefore suffer from significant growth retardation during therapy. Alternative therapy concepts are therefore urgently needed. In the proposed project, the influences of different TKIs on bone metabolism and cartilage differentiation will be investigated.

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