J110: Epithelial telomere shortening in the pathogenesis of ulcerative colitis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.11.2024
End date : 30.04.2027
Project details
Scientific Abstract
Various factors contribute to the pathogenesis of ulcerative colitis (UC). Importantly, telomere shortening is often observed in intestinal epithelial cells (IECs) of patients with UC. Nevertheless, the functional role telomere length in IECs is poorly understood. This project aims to evaluate how telomere length is involved in the regulation of pro-inflammatory pathways and affects the barrier integrity in patients with UC.
Involved:
Oana-Maria Thoma
Project Leader
Stephan Patrick Rosshart
Project Member
Leonhard Möckl
Project Member
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology
Professur für Mikrobiomik
Professur für Nanooptische Bildgebung
