P179: Muscle tissue engineering on PCL collagen I-PANi nanofiber scaffolds in the EPI loop model
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.08.2025
End date : 31.07.2026
Project details
Scientific Abstract
The aim of this project is to generate differentiated, axially vascularized and neurotized skeletal muscle tissue from ADSC and myoblasts on PCL-collagen I-(PANi)-nanofiber scaffolds. For this, seeded nanofiber scaffolds of PCL-collagen I with and without Polyanilin (4%) will be implanted in the neurotized vascular loop model of the rat for 6 weeks. Afterwards the myogenic differentiation will be analysed with the hypothesis, that the addition of PANi (4%) improves myogenic differentiation.
