P168: Crosstalk between T cells subtypes and fibroblast subsets in skin autoimmunity
FAU own research funding: EFI / IZKF / EAM ...
Start date : 21.02.2025
End date : 20.02.2026
Project details
Scientific Abstract
Skin autoimmunity consist in an aberrant immune response involving complex interactions between immune and stromal cells. Systemic sclerosis (SSc) is a skin autoimmune disorder with primary fibrotic components. Distinct fibroblasts subsets relevant in SSc have been identified, but to date is not known their spatial relationships with immune cells. Their role in SLE is also unknown. We plan to use a spatial multi-omics approach to better understand these processes.
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
