DOTting the path to doom: how acceleration of histone methylation leads to leukemia

Bach C, Slany R (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Cancer Cell Elsevier (Cell Press)

Book Volume: 26

Pages Range: 781-2

Journal Issue: 6

DOI: 10.1016/j.ccell.2014.11.004

Abstract

Epigenetic control mechanisms are central to normal and malignant hematopoiesis. In this issue of Cancer Cell, Deshpande and colleagues demonstrate that AF10, an interaction partner of the histone methyltransferase DOT1L, is essential for efficient H3K79 methylation, thus regulating HOX-gene transcription and transformation in myeloid leukemia.

Authors with CRIS profile

Christian Bach Department of Medicine 5 – Haematology and Oncology Robert Slany Lehrstuhl für Genetik

How to cite

APA:

Bach, C., & Slany, R. (2014). DOTting the path to doom: how acceleration of histone methylation leads to leukemia. Cancer Cell, 26(6), 781-2. https://doi.org/10.1016/j.ccell.2014.11.004

MLA:

Bach, Christian, and Robert Slany. "DOTting the path to doom: how acceleration of histone methylation leads to leukemia." Cancer Cell 26.6 (2014): 781-2.

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