Osteoarthritis research priorities: a report from a EULAR ad hoc expert committee

Conaghan PG, Kloppenburg M, Schett G, Bijlsma JWJ (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Annals of the Rheumatic Diseases BMJ Publishing Group

Publisher: BMJ Publishing Group

Book Volume: 73

Pages Range: 1442-5

Journal Issue: 8

DOI: 10.1136/annrheumdis-2013-204660

Abstract

Osteoarthritis (OA) currently affects over 40 million Europeans, with its associated personal suffering and significant economic burden for health systems set to dramatically escalate in a rapidly ageing Europe. Given the very limited effective therapeutic options for OA, the European League Against Rheumatism (EULAR) created an ad hoc committee of OA researchers, clinicians and patients to consider a research agenda focussed on the areas of epidemiology, pathogenesis, imaging and biomarkers, and therapies. The committee deliberated and listed research needs in these areas and also established some cross-area priority themes: predictors of OA progression, especially where this might enable stratified interventions; understanding mechanisms of OA pain; improved understanding of tissue communication in a process where multiple tissue pathologies are common; developing concepts of, and consequently interventions for, early OA where both pain and structural processes may be more effectively targeted than in typical clinical presentations; and the need for new treatment strategies, with examples discussed on pathology-targeted therapies and optimal combinations of therapies. This research agenda should provide useful guidance for all researchers in this field and hopefully lead to improved OA care.

Authors with CRIS profile

Georg Schett Lehrstuhl für Innere Medizin III

Involved external institutions

University of Leeds GB United Kingdom (GB) Leiden University NL Netherlands (NL) University Medical Centre Utrecht (UMC Utrecht) NL Netherlands (NL)

How to cite

APA:

Conaghan, P.G., Kloppenburg, M., Schett, G., & Bijlsma, J.W.J. (2014). Osteoarthritis research priorities: a report from a EULAR ad hoc expert committee. Annals of the Rheumatic Diseases, 73(8), 1442-5. https://doi.org/10.1136/annrheumdis-2013-204660

MLA:

Conaghan, Philip G., et al. "Osteoarthritis research priorities: a report from a EULAR ad hoc expert committee." Annals of the Rheumatic Diseases 73.8 (2014): 1442-5.

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