Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis

Becker M, Graf N, Sauter R, Allanore Y, Curram J, Denton CP, Khanna D, Matucci-Cerinic M, Pena JDO, Pope JE, Distler O, Matucci-Cerinic M, Guiducci S, Walker U, Jaeger V, Bannert B, Lapadula G, Becvarare R, Cutolo M, Valentini G, Siegert E, Rednic S, Allanore Y, Montecucco C, Carreira PE, Novak S, Czirjak L, Varju C, Chizzolini C, Allai D, Kucharz EJ, Cozzi F, Rozman B, Mallia C, Gabrielli A, Bancel DF, Airo P, Hesselstrand R, Martinovic D, Balbir-Gurman A, Braun-Moscovici Y, Hunzelmann N, Pellerito R, Caramaschi P, Black C, Damjanov N, Henes J, Ortiz Santamaria V, Heitmann S, Seidel M, Pereira Da Silva JA, Stamenkovic B, Selmi CF, Tikly M, Denisov LN, Mueller-Ladner U, Engelhart M, Hachulla E, Riccieri V, Ionescu RM, Mihai C, Sunderkoetter C, Kuhn A, Schett G, Distler J, Meroni P, Ingegnoli F, Mouthon L, De Keyser F, Smith V, Cantatore FP, Corrado A, Ullman S, Iversen L, Pozzi MR, Eyerich K, Hein R, Knott E, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Madej M, Jose Alegre-Sancho J, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Anne E, Westhovens R, De Langhe E, Lenaerts J, Anic B, Baresic M, Mayer M, Uprus M, Otsa K, Yavuz S, Radominski SC, Mueller CDS, Azevedo VF, Popa S, Zenone T, Stebbings S, Highton J, Mathieu A, Vacca A, Stamp L, Chapman P, O'Donnell J, Solanki K, Doube A, Veale D, O'Rourke M, Loyo E, Li M, Rosato E, Amoroso A, Gigante A, Oksel F, Yargucu F, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Foti R, Visalli E, Benenati A, Amato G, Ancuta C, Chirieac R, Villiger P, Adler S, Dan D, De La Pena Lefebvre PG, Rodriguez Rubio S, Valero Exposito M, Sibilia J, Chatelus E, Gottenberg JE, Chifflot H, Litinsky I, Del Galdo F, Venalis A, Saketkoo LA, Lasky JA, Kerzberg E, Montoya F, Cosentino V, Limonta M, Brucato AL, Lupi E, Spertini F, Ribi C, Buss G, Martin T, Guffroy A, Poindron V, Chung L, Schmeiser T, Zebryk P, Riso N, Riemekasten G, Rezus E, Puttini PS (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Annals of the Rheumatic Diseases BMJ Publishing Group

Book Volume: 78

Pages Range: 1242-1248

Journal Issue: 9

DOI: 10.1136/annrheumdis-2019-215145

Abstract

Objectives Mortality and worsening of organ function are desirable endpoints for clinical trials in systemic sclerosis (SSc). The aim of this study was to identify factors that allow enrichment of patients with these endpoints, in a population of patients from the European Scleroderma Trials and Research group database.

Authors with CRIS profile

Georg Schett Lehrstuhl für Innere Medizin III Jörg Distler Professur für Molekulare Mechanismen der Organfibrose Claudia Günther

Involved external institutions

Universitätsspital Basel University of Pécs / Pécsi Tudományegyetem Geneva University Hospitals / Hôpitaux universitaires de Genève (HUG) Bayer Plc Hospital Universitario 12 de Octubre University of Paris 5 - René Descartes / Université Paris V René Descartes graf biostatistics Charité - Universitätsmedizin Berlin Univerzita Karlova v Praze / Charles University in Prague Clinical Hospital Center Rijeka / Klinički bolnički centar Rijeka University College London (UCL) University of Padua / Universita degli Studi di Padova Università degli Studi di Firenze / University of Florence Universitätsspital Zürich (USZ) Western University University of Genova / Università degli Studi di Genova Policlinico San Matteo Pavia Fondazione IRCCS University of Michigan Università Politecnica delle Marche (UNIVPM) / Marche Polytechnic University Iuliu Hațieganu University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie "Iuliu Hațieganu" (UMF Cluj) Bayer Corporation Ljubljana University Medical Centre (Ljubljana UMC) / Univerzitetni klinični center Ljubljana Medical University of Silesia in Katowice / Śląski Uniwersytet Medyczny w Katowicach (SUM) Hôpital Cochin University of Bari Aldo Moro / Università degli Studi di Bari Aldo Moro University of Oxford Rambam Health Care Campus Hôpital Claude Huriez Wrocław Medical University / Uniwersytet Medyczny we Wrocławiu Gentofte Hospital Kerckhoff-Klinik Universitätsklinikum Tübingen Chris Hani Baragwanath Hospital endokrinologikum Frankfurt am Main Università degli studi di Milano Universitätsklinikum Carl Gustav Carus Dresden East Tallinn Central Hospital Copenhagen University Hospital Universidade Federal do Paraná (UFPR) Skåne University Hospital / Skånes universitetssjukhus Technische Universität München (TUM) University of Zagreb / Sveučilište u Zagrebu L'Ospedale Mauriziano di Torino Universitätsklinikum Köln Hospital General de Granollers Università degli studi "La Sapienza" University Hospital Leuven (UZ) / Universitaire ziekenhuizen Leuven University of Foggia / Università degli studi di Foggia University Hospital Split Westfälische Wilhelms-Universität (WWU) Münster Hospital Clínico Universitario de Valencia Universiteit Gent (UGent) / Ghent University Hôpital civil Ospedale Liriuniti Tulane University V.A. Nasonova Research Institute of Rheumatology Universidad de Buenos Aires (UBA) / University of Buenos Aires Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Spitalul Clinic de Urgenta "Sf. Pantelimon" Tel Aviv Sourasky Medical Center / Ichilov Hospital University of Otago Luigi Sacco Hospital Hospital Curry Cabral Hospital Universitario HM Sanchinarro Università degli Studi di Cagliari Ege University / Ege Üniversitesi Universitatea „Alexandru Ioan Cuza” din Iași Timofei Moșneaga Republican Clinical Hospital Universität Bern Grigore T. Popa University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie "Grigore T. Popa" (UMF Iași) Stanford University Universitätsklinikum Schleswig-Holstein (UKSH) Hospital Jose Maria Cabral Y Baez St Vincent's University Hospital Hôpitaux universitaires de Strasbourg (HUS) / University Hospital Strasbourg University of Waikato Poznan University of Medical Sciences / Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu Krankenhaus St. Josef Azienda Ospedaliero Universitaria "Policlinico - Vittorio Emanuele" Assistance Publique-Hôpitaux de Paris (AP-HP) Azienda Ospedaliera San Gerardo (ASST Monza) University of Leeds Spitalul Clinic Dr. I. Cantacuzino Peking Union Medical College / 北京协和医学院 Universitätsklinikum Bonn University of Verona / Università degli Studi di Verona Carol Davila University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie „Carol Davila” (UMF București) Marmara University Marienhospital Stuttgart Universidade de Coimbra

How to cite

APA:

Becker, M., Graf, N., Sauter, R., Allanore, Y., Curram, J., Denton, C.P.,... Puttini, P.S. (2019). Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis. Annals of the Rheumatic Diseases, 78(9), 1242-1248. https://doi.org/10.1136/annrheumdis-2019-215145

MLA:

Becker, Mike, et al. "Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis." Annals of the Rheumatic Diseases 78.9 (2019): 1242-1248.

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