Dong H, Virtanen S (2021)
Publication Type: Journal article
Publication year: 2021
DOI: 10.1002/jbm.b.34901
Zinc is emerging as a promising biodegradable metal for temporary implant applications. In this work, we investigate the influence of bovine serum albumin (BSA)—the most abundant blood protein in simulated body fluid (SBF) on degradation of pure Zn via electrochemical measurements and long-term immersion. Electrochemical experiments indicate a decrease of the corrosion rate of bare Zn with increasing BSA concentration in solution for short-term exposures. Samples were characterized with scanning electron microscope (SEM) (including energy dispersive spectroscopy [EDS], X-ray photoelectron spectroscopy [XPS], Fourier transform infrared spectroscopy [FTIR], and time-of-flight secondary ion mass spectrometry [TOF-SIMS]) after immersion up to 21 days. Presence of BSA in the electrolyte, decrease the amount of Ca-phosphate precipitation on Zn surface. However, a more compact surface layer formed in the presence of BSA in solution. Most noteworthy, in long-term exposures, BSA enhances localized corrosion of Zn—such detrimental localized attack was not observed in BSA-free solution. We suggest that a sealed space forming between the Zn substrate and a protein adsorption layer restricts mass transport, thus triggering localized corrosion of Zn.
APA:
Dong, H., & Virtanen, S. (2021). Influence of bovine serum albumin on biodegradation behavior of pure Zn. Journal of Biomedical Materials Research Part B: Applied Biomaterials. https://doi.org/10.1002/jbm.b.34901
MLA:
Dong, Hongzhou, and Sannakaisa Virtanen. "Influence of bovine serum albumin on biodegradation behavior of pure Zn." Journal of Biomedical Materials Research Part B: Applied Biomaterials (2021).
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