Mesoporous one-component gold microshells as 3d sers substrates
Vikulina AS, Stetsyura IY, Onses MS, Yilmaz E, Skirtach AG, Volodkin D (2021)
Publication Type: Journal article
Publication year: 2021
Journal
Book Volume: 11
Article Number: 380
Journal Issue: 10
DOI: 10.3390/bios11100380
Abstract
Surface-enhanced Raman scattering (SERS) is a powerful analytical tool for label-free analysis that has found a broad spectrum of applications in material, chemical, and biomedical sciences. In recent years, a great interest has been witnessed in the rational design of SERS substrates to amplify Raman signals and optionally allow for the selective detection of analytes, which is especially essential and challenging for biomedical applications. In this study, hard templating of noble metals is proposed as a novel approach for the design of one-component tailor-made SERS platforms. Porous Au microparticles were fabricated via dual ex situ adsorption of Au nanoparticles and in situ reduction of HAuCl4 on mesoporous sacrificial microcrystals of vaterite CaCO3. Elimination of the microcrystals at mild conditions resulted in the formation of stable mesoporous one-component Au microshells. SERS performance of the microshells at very low 0.4 µW laser power was probed using rhodamine B and bovine serum albumin showing enhancement factors of 2 × 108 and 8 × 108, respectively. The proposed strategy opens broad avenues for the design and scalable fabrication of one-component porous metal particles that can serve as superior SERS platforms possessing both excellent plasmonic properties and the possibility of selective inclusion of analyte molecules and/or SERS nanotags for highly specific SERS analysis.
Involved external institutions
Max-Planck-Institut für Kolloid- und Grenzflächenforschung / Max Planck Institute of Colloids and Interfaces
Germany (DE)
Fraunhofer-Institut für Zelltherapie und Immunologie (IZI)
Germany (DE)
Erciyes University / Erciyes Üniversitesi
Turkey (TR)
Universiteit Gent (UGent) / Ghent University
Belgium (BE)
Nottingham Trent University
United Kingdom (GB)
Germany (DE)
Fraunhofer-Institut für Zelltherapie und Immunologie (IZI)
Germany (DE)
Erciyes University / Erciyes Üniversitesi
Turkey (TR)
Universiteit Gent (UGent) / Ghent University
Belgium (BE)
Nottingham Trent University
United Kingdom (GB)
How to cite
APA:
Vikulina, A.S., Stetsyura, I.Y., Onses, M.S., Yilmaz, E., Skirtach, A.G., & Volodkin, D. (2021). Mesoporous one-component gold microshells as 3d sers substrates. Biosensors, 11(10). https://doi.org/10.3390/bios11100380
MLA:
Vikulina, Anna S., et al. "Mesoporous one-component gold microshells as 3d sers substrates." Biosensors 11.10 (2021).
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