Wüst W, May M, Scharf M, Layritz C, Eisentopf J, Ropers D, Pflederer T, Uder M, Achenbach S, Lell M (2013)
Publication Type: Journal article
Publication year: 2013
Book Volume: 7
Pages Range: 319-325
Journal Issue: 5
DOI: 10.1016/j.jcct.2013.08.012
Background: Different iterative reconstruction (IR) techniques compensate increased noise from lower tube current-time product settings, yet the differences between IR settings remain unclear. Objective: Aim of this study was to test whether different IR settings have a clinically relevant influence on image quality and on the diagnostic accuracy of low-dose CT angiography in patients with a stent. Methods: Forty-two patients with 73 coronary stents were prospectively enrolled. Data were acquired with dual-source CT, and images were reconstructed with standard filtered back projection (FBP) and raw data-based IR with different settings (I3, I4, I5). Quantitative parameters, including CT-attenuation, noise, signal-to-noise ratio, contrast-to-noise ratio, as well as the presence of in-stent stenosis > 50% were determined. All patients had invasive angiography as reference standard. Results: Mean effective dose was 0.32 ± 0.02 mSv. Image noise decreased significantly compared with FBP (I3= 29%; I4= 38% and I5= 45%), whereas signal-to-noise and contrast-to-noise ratios increased significantly (all IR settings P <.01). Subjective image quality was superior with all IR settings (P < .01). FBP sensitivity, specificity, positive predictive value, and negative predictive value were 83%, 71%, 36%, and 96% per stent compared with 100%, 76%, 44%, and 100%, respectively, in IR reconstructions independent of the IR setting applied. Conclusion: In low-dose coronary CT angiography, higher IR settings significantly improved subjective and objective image quality but had no effect on accuracy. © 2013 Society of Cardiovascular Computed Tomography.
APA:
Wüst, W., May, M., Scharf, M., Layritz, C., Eisentopf, J., Ropers, D.,... Lell, M. (2013). Stent evaluation in low-dose coronary CT angiography: Effect of different iterative reconstruction settings. Journal of Cardiovascular Computed Tomography, 7(5), 319-325. https://doi.org/10.1016/j.jcct.2013.08.012
MLA:
Wüst, Wolfgang, et al. "Stent evaluation in low-dose coronary CT angiography: Effect of different iterative reconstruction settings." Journal of Cardiovascular Computed Tomography 7.5 (2013): 319-325.
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