Lu T, Wang Y, Gao F, Zhao H, Ntziachristos V, Li J (2018)
Publication Type: Conference contribution
Publication year: 2018
Publisher: SPIE
Book Volume: 10494
Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Event location: San Francisco, CA, USA
ISBN: 9781510614734
DOI: 10.1117/12.2290000
Photoacoustic mesoscopy (PAMe), offering high-resolution (sub-100-μm) and high optical contrast imaging at the depth of 1-10 mm, generally obtains massive collection data using a high-frequency focused ultrasonic transducer. The spatial impulse response (SIR) of this focused transducer causes the distortion of measured signals in both duration and amplitude. Thus, the reconstruction method considering the SIR needs to be investigated in the computation-economic way for PAMe. Here, we present a modified back-projection algorithm, by introducing a SIR-dependent calibration process using a non-satationary convolution method. The proposed method is performed on numerical simulations and phantom experiments of microspheres with diameter of both 50 μm and 100 μm, and the improvement of image fidelity of this method is proved to be evident by methodology parameters. The results demonstrate that, the images reconstructed when the SIR of transducer is accounted for have higher contrast-to-noise ratio and more reasonable spatial resolution, compared to the common back-projection algorithm.
APA:
Lu, T., Wang, Y., Gao, F., Zhao, H., Ntziachristos, V., & Li, J. (2018). Spatial-impulse-response-dependent back-projection using the non-stationary convolution in optoacoustic mesoscopy. In Lihong V. Wang, Alexander A. Oraevsky (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. San Francisco, CA, USA: SPIE.
MLA:
Lu, Tong, et al. "Spatial-impulse-response-dependent back-projection using the non-stationary convolution in optoacoustic mesoscopy." Proceedings of the Photons Plus Ultrasound: Imaging and Sensing 2018, San Francisco, CA, USA Ed. Lihong V. Wang, Alexander A. Oraevsky, SPIE, 2018.
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