Laser-induced switching of the biological activity of phosphonate molecules
Kolesnikov I, Khokhlova A, Pankin D, Pilip A, Egorova A, Zigel V, Gureev M, Leuchs G, Manshina A (2021)
Publication Type: Journal article
Publication year: 2021
Journal
Book Volume: 45
Pages Range: 15195-15199
Journal Issue: 34
DOI: 10.1039/d1nj02487f
Abstract
Butyrylcholinesterase inhibition and its enhancement as a result of laser irradiation are demonstrated for the first time for a series of phosphorylated arylaminomalonates. The effect of substituents in the phenyl group on butyrylcholinesterase inhibition and its laser-activated enhancement is revealed experimentally and confirmed by molecular dynamics and docking modelling.
Authors with CRIS profile
Involved external institutions
Saint Petersburg State University (SPbU) / Санкт-Петербургский государственный университет (СПбГУ)
Russian Federation (RU)
Russian Academy of Sciences / Росси́йская акаде́мия нау́к (RAS)
Russian Federation (RU)
I.M. Sechenov First Moscow State Medical University
Russian Federation (RU)
Max-Planck-Institut für die Physik des Lichts (MPL) / Max Planck Institute for the Science of Light
Germany (DE)
Russian Federation (RU)
Russian Academy of Sciences / Росси́йская акаде́мия нау́к (RAS)
Russian Federation (RU)
I.M. Sechenov First Moscow State Medical University
Russian Federation (RU)
Max-Planck-Institut für die Physik des Lichts (MPL) / Max Planck Institute for the Science of Light
Germany (DE)
How to cite
APA:
Kolesnikov, I., Khokhlova, A., Pankin, D., Pilip, A., Egorova, A., Zigel, V.,... Manshina, A. (2021). Laser-induced switching of the biological activity of phosphonate molecules. New Journal of Chemistry, 45(34), 15195-15199. https://doi.org/10.1039/d1nj02487f
MLA:
Kolesnikov, Ilya, et al. "Laser-induced switching of the biological activity of phosphonate molecules." New Journal of Chemistry 45.34 (2021): 15195-15199.
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