Copper(II)-Assisted Degradation of Pheophytin a by Reactive Oxygen Species

Orzeł Ł, Drzewiecka-Matuszek A, Rutkowska-Zbik D, Krasowska A, Fiedor L, van Eldik R, Stochel G (2024)

Publication Type: Journal article

Publication year: 2024

Journal

International Journal of Molecular Sciences MDPI

Book Volume: 25

Article Number: 1831

Journal Issue: 3

DOI: 10.3390/ijms25031831

Abstract

The central ion Mg2+ is responsible for the differences between chlorophyll a and its free base in their reactivity toward metal ions and thus their resistance to oxidation. We present here the results of spectroscopic (electronic absorption and emission, circular dichroism, and electron paramagnetic resonance), spectroelectrochemical, and computational (based on density functional theory) investigations into the mechanism of pheophytin, a degradation that occurs in the presence of Cu ions and O2. The processes leading to the formation of the linear form of tetrapyrrole are very complex and involve the weakening of the methine bridge due to an electron withdrawal by Cu(II) and the activation of O2, which provides protection to the free ends of the opening macrocycle. These mechanistic insights are related to the naturally occurring damage to the photosynthetic apparatus of plants growing on metal-contaminated soils.

Involved external institutions

Jagiellonian University / Uniwersytet Jagielloński (UJ) PL Poland (PL) Jerzy Haber Institute of Catalysis and Surface Chemistry (ICSC, ICSC PAS) / Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PL Poland (PL)

How to cite

APA:

Orzeł, Ł., Drzewiecka-Matuszek, A., Rutkowska-Zbik, D., Krasowska, A., Fiedor, L., van Eldik, R., & Stochel, G. (2024). Copper(II)-Assisted Degradation of Pheophytin a by Reactive Oxygen Species. International Journal of Molecular Sciences, 25(3). https://dx.doi.org/10.3390/ijms25031831

MLA:

Orzeł, Łukasz, et al. "Copper(II)-Assisted Degradation of Pheophytin a by Reactive Oxygen Species." International Journal of Molecular Sciences 25.3 (2024).

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