IMMUNOBIOLOGY OF PAPILLOMAVIRUSES AND PROSPECTS FOR VACCINATION

Pfister H (2024)


Publication Type: Authored book

Publication year: 2024

Publisher: CRC Press

ISBN: 9781040293706

DOI: 10.1201/9781003574613-12

Abstract

Papillomavirus-induced tumors usually regress spontaneously, which is assumed to have an immunological basis. This hypothesis can be substantiated both by direct examination of warts during involution and by indirect evidence from patients with an impaired immune system. Specifically, regressing flat warts show many characteristics of a cell-mediated immune reaction. Tagami et al. 1 noted an intense mononuclear cell infiltrate in the dermis and exocytosis of mononuclear cells into the epidermis, accompanied by degenerative changes and necrosis of wart cells. Macrophages attack and invade the epidermal cells and the Langerhans cells ultrastructually appear activated in these areas of the wart.

How to cite

APA:

Pfister, H. (2024). IMMUNOBIOLOGY OF PAPILLOMAVIRUSES AND PROSPECTS FOR VACCINATION. CRC Press.

MLA:

Pfister, Herbert. IMMUNOBIOLOGY OF PAPILLOMAVIRUSES AND PROSPECTS FOR VACCINATION. CRC Press, 2024.

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