Vieth M, Langner C (2010)
Publication Type: Journal article, Review article
Publication year: 2010
Book Volume: 8
Pages Range: 7-12
Journal Issue: 4
The emerging role of non-polypoid precursors of colorectal cancer has challenged the classical adenoma-carcinoma-sequence. The group of serrated lesions has been added to the classical sequence. Serrated lesions of the colon can be subdivided into the mostly harmless hyper-plastic polyp mainly found in the left hemicolon, the traditional serrated adenoma in the distal colon of elderly patients and the relatively new entity of sessile serrated lesions/adenomas. These lesions are often erroneously referred to as polpys. This is wrong since these lesions do not represent polyps but flat lesions with a mucous cap. The term "adenoma" is not correct, either, since these sessile serrated lesions show structural abnormalities but no cytological neoplasia and thus are no adenomas. The exact risk of malignant transformation is not clear at the moment. Sessile serrated lesions account for >10 % of all colon lesions and are believed to be responsible for 50 % of so-called interval carcinomas and some seem to show a very fast malignant transformation. According to the S3 DGVS guidelines, these lesions should be completely removed. Due to the diagnostic inconsistencies of gastroenterologists and pathologists international consensus meetings are needed to answer the clinical questions on frequency of malignant transformation and to identify predictive factors.
APA:
Vieth, M., & Langner, C. (2010). No confusion regarding serrated colonpolyps (K)Eine verwirrung um serratierte kolonpolypen. Journal für Gastroenterologische und Hepatologische Erkrankungen, 8(4), 7-12.
MLA:
Vieth, Michael, and C. Langner. "No confusion regarding serrated colonpolyps (K)Eine verwirrung um serratierte kolonpolypen." Journal für Gastroenterologische und Hepatologische Erkrankungen 8.4 (2010): 7-12.
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