Selecting A Digitization Device for Bone Marrow Aspirate Smears

Kock F, Pontones M, Ghete T, Metzler M, Höfener H (2025)

Publication Type: Journal article

Publication year: 2025

Journal

Laboratory Investigation Nature Publishing Group: Open Access Hybrid Model Option B

Book Volume: 105

Article Number: 104114

Journal Issue: 5

DOI: 10.1016/j.labinv.2025.104114

Abstract

The digitization of histologic specimens has become increasingly common within the last years; however, digitization of cytologic slides has its own challenges and there is little guidance on the optimal use of digitization devices for cytopathology. For the morphologic analysis of cells in, for example, bone marrow aspirate smears, different studies have used a variety of scanner setups and there is no direct comparison between those. This makes it nontrivial to choose an optimal scanner setup. This work pragmatically analyzes different whole-slide image scanners but also cost-effective light microscope solutions and identifies important aspects for the digitization of cytopathological samples. We aimed to share our experience in selecting a digitization device for generating a bone marrow aspirate data set.

Authors with CRIS profile

Martina Pontones Department of Paediatrics and Adolescent Medicine Denisia-Tabita Ghete Department of Paediatrics and Adolescent Medicine Markus Metzler Professur für Kinder- und Jugendmedizin mit dem Schwerpunkt Pädiatrische Onkologie und Hämatologie

Involved external institutions

Fraunhofer-Institut für Bildgestützte Medizin (MEVIS)

Germany (DE)

How to cite

APA:

Kock, F., Pontones, M., Ghete, T., Metzler, M., & Höfener, H. (2025). Selecting A Digitization Device for Bone Marrow Aspirate Smears. Laboratory Investigation, 105(5). https://doi.org/10.1016/j.labinv.2025.104114

MLA:

Kock, Farina, et al. "Selecting A Digitization Device for Bone Marrow Aspirate Smears." Laboratory Investigation 105.5 (2025).

BibTeX: Download