Improvement of keratorefractive lenticule creation by application of a vortex beam in an ultraviolet femtosecond laser system
Hammer CM, Zhang Y, Klafke M, Paulsen F, Lörner J (2025)
Publication Type: Journal article
Publication year: 2025
Journal
Article Number: 10.1097/j.jcrs.0000000000001643
DOI: 10.1097/j.jcrs.0000000000001643
Abstract
Purpose: To examine the effect of a vortex beam on gas formation and interface quality after keratorefractive lenticule creation with a 347 nm UV femtosecond laser. Setting: “masked for peer-review”. Design: Experimental study. Methods: Refractive corneal lenticules were created in 40 ex vivo porcine eyes with a 347 nm UV femtosecond laser. In 20 eyes, the laser was operated with a (Laguerre-Gaussian) vortex beam (generated by a spiral phase plate), and in the remaining 20 with a normal (Gaussian) beam. In each group, 12 eyes were used for histological quantification of intraoperative gas formation. The remaining 8 eyes were subjected to scanning electron microscopy after lenticule extraction to evaluate the lenticule bed morphology. The vortex group was compared morphologically and morphometrically to the normal group. Results: Application of a vortex beam significantly decreased the amount of gas produced intraoperatively. Semiquantitative 2D histomorphometrical analysis of the area occupied by gas bubbles yielded 20,156 ± 5,591 µm2/mm in the normal samples, as compared to 9,495 ± 3,966 µm2/mm in the vortex samples (p<0.001). Moreover, the lenticule beds created by a UV vortex beam were markedly smoother and more regular than those created by a normal UV laser beam. Conclusions: Operating a UV femtosecond laser with a vortex beam may significantly decrease the risk of opaque bubble layer formation and increases surgical safety and precision.
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Involved external institutions
Switzerland (CH)
Germany (DE)How to cite
APA:
Hammer, C.M., Zhang, Y., Klafke, M., Paulsen, F., & Lörner, J. (2025). Improvement of keratorefractive lenticule creation by application of a vortex beam in an ultraviolet femtosecond laser system. Journal of Cataract and Refractive Surgery. https://doi.org/10.1097/j.jcrs.0000000000001643
MLA:
Hammer, Christian M., et al. "Improvement of keratorefractive lenticule creation by application of a vortex beam in an ultraviolet femtosecond laser system." Journal of Cataract and Refractive Surgery (2025).
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